6,14-Ethenomorphinan-7-methanol,4,5-epoxy-3-hydroxy-6-methox
- 中文别名：乙烯啡
- 中文释义：乙烯啡;依托啡
- 英文别名：etorphine;
Oripavine,6,14-endo-ethylenetetrahydro-7-(1-hydroxy-1-methylbutyl);
19-Propylorvinol;
7alpha-Etorphine;
[3H]-Etorphine;
Etorphine Discontinued;
ETORPHINE;
Propylorvinol;
M99
- cas No.：14521-96-1
- 分子式：C25H33NO4
- 分子量：411.59
- 精确分子量：411.24100
- PSA：62.16000
- InChI：The Key: CAHCBJPUTCKATP-PCHUVHOCSA-N
- 分子结构式：
物化性质
- 密度：
- 1.3g/cm3
- 熔点：
- 217°C
- 沸点：
- 549.7ºC at 760 mmHg
- 闪点：
- 286.2ºC
- 折射率：
- 1.649
- 蒸汽压：
- 6.47E-13mmHg at 25°C
- 存储条件/存储方法：
- 库房低温,通风,干燥
安全信息
- 密度：
- 1.3g/cm3
- 熔点：
- 217°C
- 沸点：
- 549.7ºC at 760 mmHg
- 闪点：
- 286.2ºC
- 折射率：
- 1.649
- 蒸汽压：
- 6.47E-13mmHg at 25°C
- 存储条件/存储方法：
- 库房低温,通风,干燥
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KM8100000
- CHEMICAL NAME :
- 6,14-endo-Ethenotetrahydrooripavine, 7-alpha-(1-hydroxy-1-methylbutyl)-
- CAS REGISTRY NUMBER :
- 14521-96-1
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C25-H33-N-O4
- MOLECULAR WEIGHT :
- 411.59
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70- Volume(issue)/page/year: 6,755,1976 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 3200 ng/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - other effects on male
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 198,340,1976
