6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol,7-fluo
- 中文别名：氟西他宾; 5-氟-2,2\'-环胞苷
- 中文释义：氟西他宾;5-氟-2,2\'-环胞苷;氟西他滨
- 英文别名：Flurocitabine;
5-fluoro-arabino-O2,O2'-cyclocytidine;
Ro-21-0702;
fluoroancitabine;
5-Fluoro-2,2'-cyclocytidine;
5-fluoro-arabino-2,2'-anhydro-cytidine;
Fluorocitabin;
5-Fluor-2,2'-cyclocytidin;
AAFC
- cas No.：37717-21-8
- 分子式：C9H10FN3O4
- 分子量：243.19
- 精确分子量：243.06600
- PSA：100.59000
- InChI：The Key: PAYBYKKERMGTSS-MNCSTQPFSA-N
- 分子结构式：
物化性质
- 密度：
- 2.11g/cm3
- 沸点：
- 391.7ºC at 760mmHg
- 闪点：
- 190.7ºC
- 折射率：
- 1.813
安全信息
- 密度：
- 2.11g/cm3
- 沸点：
- 391.7ºC at 760mmHg
- 闪点：
- 190.7ºC
- 折射率：
- 1.813
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA5400000
- CHEMICAL NAME :
- Cytosine, 2,2'-anhydroarabino-5-fluoro-
- CAS REGISTRY NUMBER :
- 37717-21-8
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H10-F-N3-O4
- MOLECULAR WEIGHT :
- 243.22
- WISWESSER LINE NOTATION :
- T B556 AN CO GO IN HHTT&J D1Q EQ JZ KF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 33 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Blood - normocytic anemia Blood - leukopenia
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 23,2657,1974
