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6H-Dibenzo[a,g]quinolizine-2,9-diol,5,8,13,13a-tetrahydro-3,

  • 中文别名:金黄紫堇碱
  • 中文释义:金黄紫堇碱
  • 英文别名:(S)-scoulerine;
    l-skoulerine;
    SCOULERIN;
    Alkaloid HF-1;
    l-scoulerine;
    2,9-DIOXY-3,10-DIMETHOXYBERBINE 
  • cas No.:6451-73-6
  • 分子式:C19H21NO4
  • 分子量:327.37
  • 精确分子量:327.14700
  • PSA:62.16000
  • InChI:The Key: KNWVMRVOBAFFMH-HNNXBMFYSA-N
  • 分子结构式:

物化性质

密度:
1.37g/cm3
熔点:
192ºC
沸点:
503.3ºC at 760 mmHg
闪点:
258.2ºC
折射率:
1.679

安全信息

密度:
1.37g/cm3
熔点:
192ºC
沸点:
503.3ºC at 760 mmHg
闪点:
258.2ºC
折射率:
1.679

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DR9808600
CHEMICAL NAME :
13a-alpha-Berbine-2,9-diol, 3,10-dimethoxy-
CAS REGISTRY NUMBER :
6451-73-6
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H21-N-O4
MOLECULAR WEIGHT :
327.41
WISWESSER LINE NOTATION :
T D6 B666 KN&TT&J GO1 HQ PO1 QQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,26,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
MZUZA8 Meditsinskii Zhurnal Uzbekistana. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1957- Volume(issue)/page/year: (6),39,1977

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