- 中文别名:葡萄糖酸奎尼丁
- 中文释义:葡萄糖酸奎尼丁;喹尼丁葡糖酸盐
- 英文别名:quinidine D-gluconate;
QUINIDINE GLUCONATE - cas No.:7054-25-3
- 分子式:
C26H36N2O9
- 分子量:520.57
- 精确分子量:520.24200
- PSA:184.04000
- InChI:The Key: XHKUDCCTVQUHJQ-IFWQJVLJSA-N
- 分子结构式:
物化性质
- 熔点:
- 175-176ºC
安全信息
- 熔点:
- 175-176ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ5250000
- CAS REGISTRY NUMBER :
- 7054-25-3
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C20-H24-N2-O2.C6-H12-O7
- MOLECULAR WEIGHT :
- 520.64
- WISWESSER LINE NOTATION :
- T66 BNJ HO1 EYQ- DT66 A B CNTJ A1U1 &QVYQYQYQYQ1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 7609 mg/kg/78W-I
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, allergic (after systemic exposure)
- REFERENCE :
- AIMDAP Archives of Internal Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1908- Volume(issue)/page/year: 145,446,1985
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 337 mg/kg/17D-I
- TOXIC EFFECTS :
- Blood - changes in cell count (unspecified) Nutritional and Gross Metabolic - body temperature increase
- REFERENCE :
- AJMEAZ American Journal of Medicine. (Technical Pub., 875 Third Ave., New York, NY 10022) V.1- 1946- Volume(issue)/page/year: 77,345,1984
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 23,288,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83945 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 66 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83945 No. of Facilities: 63 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 9094 (estimated) No. of Female Employees: 8028 (estimated)