- 中文别名：氟鼠酮
- 中文释义：氟鼠灵;氟羟香豆素;氟鼠酮;3-[3-(4\'-三氟甲基苄基氧代苯-4-基)-1,2,3,4-四氢-1-萘基]-4-羟基香豆素;杀它仗
- 英文别名：flocoumafen;
STORM;
4-hydroxy-3-[(1Ξ,3Ξ)-3-(4-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-2H-1-benzopyran-2-one;
4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]-1-naphthalenyl]-2H-1-benzopyran-2-one;
Flocoumafen;
stratgem;
1RS,3SR)-1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin;
aphthyl)coumarin;
Storm(rodenticide);
4-hydroxy-3-[(1RS,3RS;
FLOCUMAFEN;
Stratagen - cas No.：90035-08-8
- 分子式：
C33H25F3O4
- 分子量：542.54400
- 精确分子量：542.17000
- PSA：59.67000
- MDL：MFCD01662724
- 分子结构式：
物化性质
- 外观与性状：
- 白色固体
- 密度：
- 1.348g/cm3
- 熔点：
- 181-191 (cis-isomer). 163-166 (trans- isomer)ºC
- 沸点：
- 640.2ºC at 760mmHg
- 闪点：
- 341ºC
- 折射率：
- 1.629
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开储运
- 其它信息：
1.性状：白色粉末
2.相对密度：1.23
3.熔点（ºC）：161~162
4.闪点（ºC）：200
5.溶解性：溶于丙酮、乙醇、氯仿、二甲苯等有机溶剂。
安全信息
- 外观与性状：
- 白色固体
- 密度：
- 1.348g/cm3
- 熔点：
- 181-191 (cis-isomer). 163-166 (trans- isomer)ºC
- 沸点：
- 640.2ºC at 760mmHg
- 闪点：
- 341ºC
- 折射率：
- 1.629
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开储运
- 其它信息：
1.性状：白色粉末
2.相对密度：1.23
3.熔点（ºC）：161~162
4.闪点（ºC）：200
5.溶解性：溶于丙酮、乙醇、氯仿、二甲苯等有机溶剂。
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DJ3100300
- CHEMICAL NAME :
- 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-((4-(trifluorome thyl)phenyl) methoxy)phenyl)-1-naphthalenyl)-
- CAS REGISTRY NUMBER :
- 90035-08-8
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C33-H25-F3-O4
- MOLECULAR WEIGHT :
- 542.58
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C285,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 75 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 700 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - pig
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- >100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - gerbil
- DOSE/DURATION :
- 180 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,398,1991 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2500 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- JANREH Journal of Applied Animal Research. (Garuda Scientific Publications, 151, Janakpuri, Izatnagar, 243122, India) V.1- 1992- Volume(issue)/page/year: 2,81,1992
- 毒理学数据：
大鼠、小鼠、兔经口LD50(mg/kg)：0.25、0．8、0．2。对皮肤和眼睛无刺激作用。虹鳟鱼LD50为0.0091mg/L，野鸭经口LD50为1.7mg/kg。
分子结构与计算化学数据
分子结构数据
1、 摩尔折射率：143.02
2、 摩尔体积（cm3/mol）：402.3
3、 等张比容（90.2K）：1082.2
4、 表面张力（dyne/cm）：52.3
5、 极化率（10-24cm3）：56.69
计算化学数据
1.疏水参数计算参考值（XlogP）:7.7
2.氢键供体数量:1
3.氢键受体数量:7
4.可旋转化学键数量:5
5.互变异构体数量:3
6.拓扑分子极性表面积55.8
7.重原子数量:40
8.表面电荷:0
9.复杂度:915
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:2
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1